Both players had to wait until Tuesday to be added to the Major League roster, because they were optioned to Triple-A Tacoma last week. Optioned players aren't eligible to return for at least 10 days, unless the Minor League club ends its season prior to that span. Tacoma played its final game on Monday.
Paxton was optioned to Tacoma after throwing 6 2/3 scoreless innings against the Rangers last Tuesday in a move designed strictly to open a temporary 25-man roster spot. Paxton didn't pitch for Tacoma, and he returns on schedule for Tuesday's start.
The 25-year-old southpaw is 4-1 with a 1.83 ERA in seven starts for Seattle, including a 2-1 record and 1.65 ERA in five August starts since missing four months with shoulder problems.
Ramirez, 24, returns for his seventh stint with the Mariners this season. He's 1-6 with a 5.21 ERA in 14 starts with Seattle and 6-5 with a 3.65 ERA in 15 games (14 starts) for Tacoma. Ramirez was optioned to Tacoma after giving up 10 runs on nine hits in three-plus innings in a 12-4 loss to the Rangers on Wednesday.
Seven other players were promoted from Tacoma prior to Monday's game: outfielders Corey Hart and Stefen Romero, first baseman Justin Smoak, pitchers Taijuan Walker, Lucas Luetge and Carson Smith and catcher Humberto Quintero.
Greg Johns is a reporter for MLB.com. Follow him on Twitter @GregJohnsMLB as well as his Mariners Musings blog. This story was not subject to the approval of Major League Baseball or its clubs.