"He said something to the umpire, and the umpire didn't like it," said Mariners manager Lloyd McClendon.
It was the first ejection of Miller's Major League career. The 24-year-old has played 156 games over the past two seasons and is hitting .206 in 80 games this season, with eight home runs and 24 RBIs.
Veteran utility infielder Willie Bloomquist replaced Miller in the fifth inning.
Greg Johns is a reporter for MLB.com. Follow him on Twitter @GregJohnsMLB as well as his Mariners Musings blog. This story was not subject to the approval of Major League Baseball or its clubs.