The 23-year-old Nicaraguan pitched 5 1/3 innings for Everett in Wednesday's 7-6 victory over Vancouver, allowing two runs (one earned) on six hits with one walk and 10 strikeouts in a no-decision.
Ramirez missed the first three months of the season while coming back from a strained elbow, pitched seven games for Triple-A Tacoma and then gave up seven runs and six hits with four walks in 4 2/3 innings in an 8-7 loss to the Red Sox in his first game for the Mariners.
If the youngster hadn't been sent down to Everett, he'd have gone 11 days between starts before his turn came back up on Tuesday against the Indians. Tacoma was on its own All-Star break on Wednesday, so Everett provided the best option.
The Mariners are carrying an extra pitcher in the bullpen since Ramirez was sent down, so they'll likely option one of their relievers to Tacoma to make room on the 25-man roster. Bobby LaFromboise and Hector Noesi were recalled from Tacoma when Ramirez was optioned out along with Blake Beavan, but neither pitched in the three-game weekend sweep of the Angels.
Greg Johns is a reporter for MLB.com. Follow him on Twitter @GregJohnsMLB as well as his Mariners Musings blog. This story was not subject to the approval of Major League Baseball or its clubs.